Yea I should have put an asterisk.
I’d go further and say you should ask a pharmacist about questions like these. Even better is to ask a compounding pharmacist, as a doctor or retail pharmacist might just recite the pharmacopeia to you while a compounding pharmacist will probably explain in more detail (likely as a play to offer their services lol).
So it technically depends on the extended release formulation, so from a layman’s perspective, yes you should likely ask your doctor or even better ask a compounding pharmacist (as a general rule if you have questions about medication you’re better off asking a pharmacist rather than a doctor.)
Given that…
From a technical perspective the only definition of extended release is a lag phase after ingestion. This means there’s no immediately discernable difference between delayed release through anti-dissolution coating and slow dissolution through a hard-to-dissolve substance. (Even when you read something like two different pills saying delayed release vs extended release, there’s no legal difference and the FDA doesn’t give a fuck about the naming. This might be different in other countries so Americans benefit from other Country’s health systems in naming. I’m not sure.)
Coating-type pill formulations should not be crushed.
Suspension-type formulations actually can be crushed to a certain degree. Typically humans aren’t going at the pills like crazy in a mortar and pestle and don’t have the strength to separate the suspension properly so it’ll still have a slowed release effect. But yea if you smash them too hard then yea you can actually mess up the way that works.
By the way if anyone’s curious yes you can crush up Viagra, put it in Vaseline, and use it as a cream.
Yes you can put it there, and yes it’s effective.
I’ve done it multiple times for people that would regularly go over that five hour limit, because skin absorption is slower and weaker than intestinal absorption.
Only EC(Enteric Coated) pills and capsule interiors cause they protect the pill against stomach acid until it reaches the intestine.
If it’s got a shiny exterior like an Advil it’s Enteric coated. If it’s a capsule with EC granules you’re gonna have a hard time crushing it anyway.
You’re probably not going to have a problem with those though because Enteric coating is super sweet and capsules are usually neutral in flavor, so there’s not much reason to try and hide the bitterness. For everything else there’s no real functional difference between a smashed pill and a whole pill in your stomach.
Edit: You should definitely consult with a pharmacist or even better a compounding pharmacist about this if you’re not sure what kind of pill you’re looking at, though.
Former pharmacy tech here, 8 years compounding pharmacy.
Get a mortar and pestle, crush it up and put it in whatever.
If not then use yogurt or something gooey.
For the usability of the clock, likely nothing.
I did mention In another comment that there are a number of advantages a round clockface provides to the creation of the clock, however.
Yea that’s kind of what I was thinking when I said eventually handwriting will go the same way.
If people never encounter it and do all their writing on keyboards, it’ll eventually be a useless skill as well.
From a practicality standpoint, a round clockface is easier to create a mechanical drive system for.
You can create a digital mechanical face (see: Flipboard style numerical displays) but they usually require more gears and are more susceptible to wear and tear than the gears of a round clock face.
The simplest designs for mechanical digital displays actually just take 24 hour and 60 minute/second circular displays and hide the other numerals as the clock face spins around. Technically this I suppose counts as both analog and digital?
Example:
As for electronic displays? Nah not much of a reason to use a round display unless again, you have an electric-mechanical drive and want to save on gears and parts.
It floors me just how many people in this thread feel like analog clock reading is a useless/outdated skill.
But I’m of the opinion that there’s no such thing as a truly outdated and useless skill, so I’m not sure I have the capability to empathize with those people…
How so?
I genuinely don’t understand the clock-face-reading-is-a-useless-skill opinion so both seem equally important to me.
There’s nothing stopping an analog clock face from representing 24h time:
I wonder how many people feel this way about writing when everyone just types/texts everything.
Why are they targeting Zenimax so heavily, don’t they have 50 other acquisitions they can suck the blood from
Tango closed cause it was the one of the only studios under Zenimax that wasn’t currently making a game with “executive producer: Todd Howard” squirted all over it
The steam deck’s pause-on-power-off has been very convenient for games like this
You should play voices of the void then. Game is chock full of random spooks with lots of very quiet and relaxing downtime, so they hit pretty hard when they happen.