The reason you do stuff in a venv is to isolate that environment from other python projects on your system, so one Python project doesn’t break another. I use Docker for similar reasons for a lot of non-Python projects.
A lot of Python projects involve specific versions of libraries, because things break. I’ve had similar issues with non-Python projects. I’m not sure I’d say Python is particularly worse about it.
There are tools in place that can make the sharing of Python projects incredibly easy and portable and consistent, but I only ever see the best maintained projects using them unfortunately.
DLSS is extremely noticeable to me at stronger levels. I usually turn it on but keep it set to “quality” instead of “performance”. It’s still slightly noticeable but not that bad at that setting.
Stronger DLSS just looks like blurry mush to me.